인공우식 법랑질에 대한 불소함유치약의 효과
Effect of Fluoride Dentifrices on subsurface Enamel Caries
강충희, 심영자, 한승렬,
소속 상세정보
강충희 ( ) - 전남대학교 치과대학 예방치과학교실
심영자 ( ) - Indiana University School of Dentistry Oral Health Research Institute
한승렬 ( ) - 단국대학교 치과대학 예방치과학교실
KMID : 0355419960200010001
Abstract
The purposes of this study were to determine the efficacy of fluoride dentifrices for the promotion of fluoride uptake, remineralization and/or demineralization of subsurface lesion under dynamic conditions of simulating in vivo caries formation. Seventy two human enamel cores were prepared and fixed on plexiglass rods and randomly coded with two digit numbers. Subsurface lesions were created by exposing the cores to a solution containing 0.1M lactic acid, 0.2% Carbopol, pH 5.0, with 50% HAP saturation for 96 hours. After surface hardness numbers (VHN) were determined, the specimens were assigned to 6 test groups of 12 specimens each by randomized blocks with VHN stratification. The 6 test groups tested in this study were placebo, 250, 600 or 1,100 ppm of fluoride ions from sodium monofluorophosphate (MFP) in dicalcium phosphate dehydrate (DCPD) abrasive system and 1,100 ppm fluoride from NaF/Silica dentifrices, and 1,000 ppm MFP+Bamboo salt. The specimens were provided with 4 daily 1-minute dentifrice treatments at 9 a.m., 10 a.m., 4 p.m. and 5 p.m. After respective dentifrice slurry treatment, the specimens were exposed to a mixture of saliva and synthetic
saliva(1:1). The specimens were then exposed to demineralization solution for 4 hours for acid challenge. The cycles were repeated 20 days at which time their VHNs were again randomly determined in the proximity of the initial areas tested of the same specimens. The VHNs were decoded by treatment groups. The specimens were cut in half for characterization of lesion depth under confocal laser scanning microscope. The changes of surface hardness in terms of Mean VHN (SD) were; 12.95(9.01), 11.36(7.26), 15.49(3.99), 21.71(8.54), 23.51(6.62), Mean lesion depth(SD) in terms of mm were 48.44(11.0), 53.92(6.93), 52.54(6.29), 46.84(5.44), 44.58(6.86) and 46.83(4.01) from placebo, 250 ppm (MFP), 600 ppm (MFP), 1,100 ppm (NaF), 1,000 ppm (MFP + Bamboo salt), 1,100 ppm (MFP) respectively. These results were then statistically analyzed using ANOVA for the significance of differences among treatment groups. The results indicated that (1) the delta VHNs of both groups treated with 1,100 ppm fluoride dentifrices were significantly higher (p<0.05) than placebo, 250 ppm or 600 ppm fluoride groups; (2) the lesion depths of groups treated with 1,100 ppm fluoride dentifrices were significantly more shallow (p<0.05) than 250 ppm or 600 ppm fluoride groups.
키워드
초기법랑질 우식;불쇠치약;재광화
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